A weight-loss injection is set to be offered on the NHS in England to more than a million people considered at high risk of further heart attacks or strokes. Health guidance recommends the treatment for individuals who are overweight and have already experienced serious cardiovascular conditions or circulation problems.

The medication will be prescribed alongside existing treatments, such as cholesterol-lowering drugs, and supported by advice on diet and exercise. Clinical trials involving large numbers of participants have shown the injections can significantly lower the chances of future heart-related events, with benefits appearing even before major weight loss occurs.

The treatment works by mimicking a natural hormone that helps control appetite and slows digestion, making people feel fuller for longer. Patients will be able to administer the injection themselves using a pen device at home. However, some may experience side effects including nausea, bloating or discomfort.

Access to the drug is currently limited to a fixed treatment period, and its long-term effects are still being studied. Experts stress the importance of maintaining physical activity, particularly strength-based exercise, to protect muscle health. The rollout is expected to begin in the coming months, following an agreement to ensure the treatment is cost-effective for the NHS.