Rob Burrow, a former rugby league player, has died at the age of 41 following a four-year battle with Motor Neurone Disease (MND). His death brings attention to the severity of MND and the ongoing search for a cure. Motor Neurone Disease (MND) affects nerves in the brain and spinal cord, leading to muscle weakness and stiffness. This impacts walking, talking, eating, and breathing. The disease progresses rapidly, with over half of those affected dying within two years of diagnosis.

The cause of MND is unclear, likely involving genetic and lifestyle factors. About one in 300 people will develop MND, most commonly those over 50. Around 10% of cases involve specific genetic mutations, often with a family history. Common symptoms include muscle weakness, cramps, stiff joints, speech difficulties, and issues with swallowing and eating. The disease progresses at different rates for each person.

There is no cure yet for MND. In the UK, the only approved drug is Riluzole, which may extend survival by a few months. New treatments like Tofersen show promise but are not yet available in the UK. Strenuous exercise is linked to an increased risk of MND, especially in elite athletes. Research suggests strenuous activity can trigger the disease in genetically predisposed individuals.

Since his diagnosis, Rob Burrows has raised more than £15million for charity and made an MBE in the 2021 New Years Honours. In a statement, his wife Lindsey Burrow called him "simply the best" and said he was "our hero". She then followed on to say, "Although we knew this day would arrive, I am somehow still feeling at a loss for words that our loving, kind and caring husband and father has departed," she said.